Treating Special Populations with Hypertension: Is a Two-Drug or Fixed-Dose Combination Therapy Appropriate Initial Treatment in Hypertension?
نویسندگان
چکیده
Currently, physicians are utilizing one or more antihypertensive medications, with lifestyle modifications, to get BP controlled to levels below 140/90 mm Hg. Both in clinical practice and in clinical trials a majority of patients may require two or more antihypertensive drugs to be effectively controlled. Thus, the clinician is challenged to determine whether one or more drugs should be started in patients with hypertension, especially in patients who are part of special populations.
منابع مشابه
Fixed-dose triple-combination treatments in the management of hypertension.
Hypertension remains uncontrolled in approximately 50% of patients with hypertension, which increases the risk of cardiovascular morbidity and mortality in these individuals. A key factor contributing to poor blood pressure (BP) control is nonadherence to prescribed antihypertensive medications. Improving patient adherence to antihypertensive therapy is the key to improving BP goal attainment. ...
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Fixed-dose combination drugs are not indicated for initial therapy of edema or hypertension. Edema or hypertension requires therapy titrated to the individual patient. If the fixed combination represents the dosage so determined, its use may be more convenient in patient management. The treatment of hypertension and edema is not static but must be reevaluated as conditions in each patient warrant.
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